Evidence Based Medicine: 6S Pyramid

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Clinical Question ​

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 Suggested Research Design(s)​

 All Clinical​

 Questions​

 Systematic review, meta-analysis​

 Therapy​

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 Randomized controlled trial (RCT), meta-analysis​

 Also: cohort study, case-control study, case series​

 Etiology​

 Randomized controlled trial (RCT), meta-analysis, cohort study​

 Also: case-control study, case series​

 Diagnosis​

 Randomized controlled trial (RCT) Also: cohort study​

 Prevention​

 Randomized controlled trial (RCT), meta-analysis Also: prospective study, cohort study, case-control study, case series​

 Prognosis​

 Cohort study​

 Also: case-control study, case series​

 Meaning​

 Qualitative study​

 Quality​

 Improvement​

 Randomized controlled trial (RCT) Also: qualitative study​

 Cost​

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 Economic evaluation​