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Evidence Based Medicine: 6S Pyramid

Find specific resources aimed to help you apply the principles of evidence based medicine

6S Pyramid

evidence pyramid

Jan Glover, David Izzo, Karen Odato, and Lei Wang. EBM levels of evidence. Accessed Sep 16, 2022. 2006-Trustees-of-Dartmouth_fig4_309734346

What type of study do I use for a certain type of PICO question?​

Clinical Question ​

 Suggested Research Design(s)​

 All Clinical​


 Systematic review, meta-analysis​


 Randomized controlled trial (RCT), meta-analysis​

 Also: cohort study, case-control study, case series​


 Randomized controlled trial (RCT), meta-analysis, cohort study​

 Also: case-control study, case series​


 Randomized controlled trial (RCT) Also: cohort study​


 Randomized controlled trial (RCT), meta-analysis Also: prospective study, cohort study, case-control study, case series​


 Cohort study​

 Also: case-control study, case series​


 Qualitative study​



 Randomized controlled trial (RCT) Also: qualitative study​


 Economic evaluation​

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Joanna Anderson
Dunbar Library 120
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